Bodywork can play a huge role in managing symptoms relating to both physical issues of the hypertonic contractions as well as the mental and sensory issues associated with touch and therapy.  The depressive nature of the disease and the isolation of physicality is a viscious circle and is one that massage therapists and bodyworkers can directly address.  It's not just about getting tight muscles to release and relax, but about getting sensory perceptions to be activated, re-firing neural pathways and getting neurons to communicate and keep their pathways communicating.  Touch is vitally important in these circumstances and just having a treatment can be a great alleviator to the isolation that these people can feel.